Phthalates are contaminants widely distributed in the food-chain, and they are considered as important environmental oestrogens in our lives. In the present study, eight strains of lactic acid bacteria were isolated for their ability to adsorb di-n-butyl-phthalate DBP , and one of the strains, Lactobacillus plantarum strain P1, was selected for more detailed analyses of its phthalate adsorption capacity in vitro. This study also evaluated the in vivo protective effects of strain P1 against DBP toxicity in rats. Strain P1 could adsorb more DBP than saline alone, and the concentration of mono-n-butyl phthalate in urine was decreased in animals receiving P1. Furthermore, oestrogenic effects of the different treatments were assessed through counting of sperm and observation of testis, and strain P1 could protect the sexual organs of male rats. Our results suggested that P1 is effective against phthalate toxicity due to its ability to adsorb DBP in vivo and could be considered as a new dietary therapeutic strategy against environmental phtalate toxicity. New titles:. Related titles:. For institutional orders, please contact sales wageningenacademic. Protective effects of Lactobacillus plantarum strain P1 against toxicity of the environmental oestrogen di-n-butyl phthalate in rats. Beneficial Microbes: 0 0 - Pages: 1 - Keywords: Lactobacillus plantarum , phthalate , adsorption , sexual development. Beneficial Microbes Beneficial Microbes. Print ISSN: Online ISSN: Institutional Offers For institutional orders, please contact sales wageningenacademic. What is this? Probiotic or synbiotic alters the gut microbiota and metabolism in a randomised controlled trial of weight management in overweight adults. Hibberd, C. Yde, M. Ziegler, A. Saarinen, S. Lahtinen, B. Stahl, H. Jensen and L. Acne vulgaris, probiotics and the gut-brain-skin axis: from anecdote to translational medicine. Bowe, N. Patel and A. The impact of meals on a probiotic during transit through a model of the human upper gastrointestinal tract. Tompkins, I. Mainville and Y. Effect of probiotic supplementation on cognitive function in children and adolescents: a systematic review of randomised trials.
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